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Dual-lifetime referencing (DLR): a powerful method for on-line measurement of internal pH in carrier-bound immobilized biocatalysts

BACKGROUND: Industrial-scale biocatalytic synthesis of fine chemicals occurs preferentially as continuous processes employing immobilized enzymes on insoluble porous carriers. Diffusional effects in these systems often create substrate and product concentration gradients between bulk liquid and the...

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Detalles Bibliográficos
Main Authors: Boniello, Caterina, Mayr, Torsten, Bolivar, Juan M, Nidetzky, Bernd
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359222/
https://ncbi.nlm.nih.gov/pubmed/22455624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-11
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