Mind bomb 1 is required for pancreatic β-cell formation

During early pancreatic development, Notch signaling represses differentiation of endocrine cells and promotes proliferation of Nkx6-1(+)Ptf1a(+) multipotent progenitor cells (MPCs). Later, antagonistic interactions between Nkx6 transcription factors and Ptf1a function to segregate MPCs into distal...

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Bibliographische Detailangaben
Hauptverfasser: Horn, Signe, Kobberup, Sune, Jørgensen, Mette C., Kalisz, Mark, Klein, Tino, Kageyama, Ryoichiro, Gegg, Moritz, Lickert, Heiko, Lindner, Jill, Magnuson, Mark A., Kong, Young-Yun, Serup, Palle, Ahnfelt-Rønne, Jonas, Jensen, Jan N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358874/
https://ncbi.nlm.nih.gov/pubmed/22529374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203605109
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