Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions

Dengue is a mosquito-borne flavivirus that is spreading at an unprecedented rate and has developed into a major health and economic burden in over 50 countries. Even though infected individuals develop potent and long-lasting serotype-specific neutralizing antibodies (Abs), the epitopes engaged by h...

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Main Authors: de Alwis, Ruklanthi, Smith, Scott A., Olivarez, Nicholas P., Messer, William B., Huynh, Jeremy P., Wahala, Wahala M. P. B., White, Laura J., Diamond, Michael S., Baric, Ralph S., Crowe, James E., de Silva, Aravinda M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358852/
https://ncbi.nlm.nih.gov/pubmed/22499787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200566109
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