HIV-1 incorporation of host-cell–derived glycosphingolipid GM3 allows for capture by mature dendritic cells

The interaction between HIV and dendritic cells (DCs) is an important early event in HIV-1 pathogenesis that leads to efficient viral dissemination. Here we demonstrate a HIV gp120-independent DC capture mechanism that uses virion-incorporated host-derived gangliosides with terminal α2–3-linked sial...

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Bibliografiska uppgifter
Huvudupphovsmän: Puryear, Wendy Blay, Yu, Xinwei, Ramirez, Nora P., Reinhard, Björn M., Gummuluru, Suryaram
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358844/
https://ncbi.nlm.nih.gov/pubmed/22529395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201104109
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