Palmitoylethanolamide Protects Against the Amyloid-β25-35-Induced Learning and Memory Impairment in Mice, an Experimental Model of Alzheimer Disease

Alzheimer disease (AD) is the most common form of neurodegenerative dementia. Amyloid-β deposition, neurofibrillary tangle formation, and neuro-inflammation are the major pathogenic mechanisms that in concert lead to memory dysfunction and decline of cognition. Palmitoylethanolamide (PEA) is the nat...

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Bibliographic Details
Main Authors: D'Agostino, Giuseppe, Russo, Roberto, Avagliano, Carmen, Cristiano, Claudia, Meli, Rosaria, Calignano, Antonio
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358748/
https://ncbi.nlm.nih.gov/pubmed/22414817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.25
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