Decreased Cocaine Motor Sensitization and Self-Administration in Mice Overexpressing Cannabinoid CB(2) Receptors

The potential involvement of the cannabinoid CB(2) receptors (CB(2)r) in the adaptive responses induced by cocaine was studied in transgenic mice overexpressing the CB(2)r (CB(2)xP) and in wild-type (WT) littermates. For this purpose, the acute and sensitized locomotor responses to cocaine, conditio...

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Detalhes bibliográficos
Main Authors: Aracil-Fernández, Auxiliadora, Trigo, José M, García-Gutiérrez, María S, Ortega-Álvaro, Antonio, Ternianov, Alexander, Navarro, Daniela, Robledo, Patricia, Berbel, Pere, Maldonado, Rafael, Manzanares, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358745/
https://ncbi.nlm.nih.gov/pubmed/22414816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.22
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