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A Single Administration of Low-Dose Varenicline Saturates α4β2(*) Nicotinic Acetylcholine Receptors in the Human Brain

The primary objective of this project was to determine the α4β2(*) nicotinic acetylcholine receptor (nAChR) occupancy in human brain of a single low dose of varenicline (0.5 mg), and to explore the relationship between receptor occupancy by varenicline and tobacco withdrawal symptoms ((*)denoting ot...

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Detalhes bibliográficos
Main Authors: Lotfipour, Shahrdad, Mandelkern, Mark, Alvarez-Estrada, Miguel, L Brody, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358744/
https://ncbi.nlm.nih.gov/pubmed/22395733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.20
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