Reiteration frequency of immunoglobulin light chain genes: further evidence for somatic generation of antibody diversity.
Methods have been developed for preparing mouse immunoglobulin light chain mRNA of better than 90% purity. Hybridization of both lambda and kappa mRNAs to excess liver DNA yielded results compatible with gene reiteration frequencies of two to three. There was no evidence of hybridization of these hi...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1976
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/813222/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.1.203 |
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