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Detection of exon skipping events in BRCA1 RNA using MLPA kit P002

A rapid and easy method to screen for aberrant cDNA would be a very useful diagnostic tool in genetics since a fraction of the DNA variants found affect RNA splicing. The currently used RT-PCR methods require new primer combinations to study each variant that might affect splicing. Since MLPA is rou...

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Bibliografiske detaljer
Main Authors: Brandão, Rita D., Tserpelis, Demis, Gómez García, Encarna, Blok, Marinus J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358555/
https://ncbi.nlm.nih.gov/pubmed/22350158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-012-1575-2
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