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ENU Mutagenesis in Mice Identifies Candidate Genes For Hypogonadism

Genome-wide mutagenesis was performed in mice to identify candidate genes for male infertility, for which the predominant causes remain idiopathic. Mice were mutagenized using N-ethyl-N-nitrosourea (ENU), bred, and screened for phenotypes associated with the male urogenital system. Fifteen heritable...

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Detalhes bibliográficos
Main Authors: Weiss, Jeffrey, Hurley, Lisa A., Harris, Rebecca M., Finlayson, Courtney, Tong, Minghan, Fisher, Lisa A., Moran, Jennifer L., Beier, David R., Mason, Christopher, Jameson, J. Larry
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358541/
https://ncbi.nlm.nih.gov/pubmed/22258617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-011-9388-5
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