Progesterone is neuroprotective against ischemic brain injury through its effects on the PI3K/Akt signaling pathway

We tested the hypothesis that the phosphatidylinositol-3 kinase (PI3K/Akt) pathway mediates some of the neuroprotective effects of progesterone (PROG) after ischemic stroke. We examined whether PROG acting through the PI3K/Akt pathway could affect the expression of vascular endothelial growth factor...

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Bibliographische Detailangaben
Hauptverfasser: Ishrat, Tauheed, Sayeed, Iqbal, Atif, Fahim, Hua, Fang, Stein, Donald G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358507/
https://ncbi.nlm.nih.gov/pubmed/22450229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.03.008
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