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Wildtype coxsackievirus infection dramatically alters the abundance, heterogeneity, and immunostimulatory capacity of conventional dendritic cells in vivo

In vitro studies have shown that enteroviruses employ strategies that may impair the ability of DCs to trigger T cell immunity, but it is unclear how these viruses affect DCs in vivo. Here, we evaluate the effects of wild-type (wt) coxsackievirus B3 on DCs in vitro and in a murine model in vivo. Alt...

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Detalhes bibliográficos
Main Authors: Kemball, Christopher C., Flynn, Claudia T., Hosking, Martin P., Botten, Jason, Whitton, J. Lindsay
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358485/
https://ncbi.nlm.nih.gov/pubmed/22551767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.04.005
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