Combined assessment of sex- and mutation-specific information for risk stratification in type 1 long QT syndrome

BACKGROUND: Men and women with type 1 long QT syndrome (LQT1) exhibit time-dependent differences in the risk for cardiac events. OBJECTIVE: We hypothesized that sex-specific risk for LQT1 is related to the location and function of the disease-causing mutation in the KCNQ1 gene. METHODS: The risk for...

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Auteurs principaux: Costa, Jason, Lopes, Coeli M., Barsheshet, Alon, Moss, Arthur J., Migdalovich, Dmitriy, Ouellet, Gregory, McNitt, Scott, Polonsky, Slava, Robinson, Jennifer L., Zareba, Wojciech, Ackerman, Michael J., Benhorin, Jesaia, Kaufman, Elizabeth S., Platonov, Pyotr G., Shimizu, Wataru, Towbin, Jeffrey A., Vincent, G. Michael, Wilde, Arthur A.M., Goldenberg, Ilan
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358462/
https://ncbi.nlm.nih.gov/pubmed/22293141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2012.01.020
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