Junín Virus Infection Activates the Type I Interferon Pathway in a RIG-I-Dependent Manner

Junín virus (JUNV), an arenavirus, is the causative agent of Argentine hemorrhagic fever, an infectious human disease with 15–30% case fatality. The pathogenesis of AHF is still not well understood. Elevated levels of interferon and cytokines are reported in AHF patients, which might be correlated t...

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Detalhes bibliográficos
Main Authors: Huang, Cheng, Kolokoltsova, Olga A., Yun, Nadezdha E., Seregin, Alexey V., Poussard, Allison L., Walker, Aida G., Brasier, Allan R., Zhao, Yingxin, Tian, Bing, de la Torre, Juan Carlos, Paessler, Slobodan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358329/
https://ncbi.nlm.nih.gov/pubmed/22629479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001659
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