Interferon-α Improves Phosphoantigen-Induced Vγ9Vδ2 T-Cells Interferon-γ Production during Chronic HCV Infection

In chronic HCV infection, treatment failure and defective host immune response highly demand improved therapy strategies. Vγ9Vδ2 T-cells may inhibit HCV replication in vitro through IFN-γ release after Phosphoantigen (PhAg) stimulation. The aim of our work was to analyze Vγ9Vδ2 T-cell functionality...

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Main Authors: Cimini, Eleonora, Bonnafous, Cécile, Bordoni, Veronica, Lalle, Eleonora, Sicard, Helene, Sacchi, Alessandra, Berno, Giulia, Gioia, Cristiana, D’Offizi, Gianpiero, Visco Comandini, Ubaldo, Vlassi, Chrysoula, Capobianchi, Maria Rosaria, Martini, Federico, Agrati, Chiara
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358305/
https://ncbi.nlm.nih.gov/pubmed/22629350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037014
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