Frequent Occurrence of Mitochondrial DNA Mutations in Barrett’s Metaplasia without the Presence of Dysplasia

BACKGROUND: Barrett's esophagus (BE) is one of the most common premalignant lesions and can progress to esophageal adenocarcinoma (EA). The numerous molecular events may play a role in the neoplastic transformation of Barrett’s mucosa such as the change of DNA ploidy, p53 mutation and alteratio...

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Main Authors: Lee, Soong, Han, Moon-Jong, Lee, Ki-Sang, Back, Seung-Chul, Hwang, David, Kim, Hwan-Young, Shin, Jong-Hee, Suh, Soon-Pal, Ryang, Dong-Wook, Kim, Hye-Ran, Shin, Myung-Geun
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358277/
https://ncbi.nlm.nih.gov/pubmed/22629421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037571
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