Selection of a MCF-7 Breast Cancer Cell Subpopulation with High Sensitivity to IL-1β: Characterization of and Correlation between Morphological and Molecular Changes Leading to Increased Invasiveness

Cancer and inflammation are closely related in tumor malignancy prognosis. Breast cancer MCF-7 cells have a poor invasive phenotype, although, under IL-1β stimulus, acquire invasive features. Cell response heterogeneity has precluded precise evaluation of the malignant transition. MCF-7A3 cells were...

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Hauptverfasser: Pérez-Yépez, Eloy Andres, Ayala-Sumuano, Jorge-Tonatiuh, Reveles-Espinoza, Alicia Maria, Meza, Isaura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357940/
https://ncbi.nlm.nih.gov/pubmed/22655200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/609148
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