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Astrocyte Mediated Protection of Fetal Cerebral Cortical Neurons from Rotenone and Paraquat

Primary cultures of fetal rat cortical neurons and astrocytes were used to test the hypothesis that astrocyte-mediated control of neuronal glutathione (GSH) is a potent factor in neuroprotection against rotenone and paraquat. In neurons, rotenone (0.025 to 1μM) for 4 and 24 h decreased viability as...

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Detalhes bibliográficos
Main Authors: Rathinam, Mary Latha, Watts, Lora Talley, Narasimhan, Madhusudhanan, Riar, Amanjot Kaur, Mahimainathan, Lenin, Henderson, George.I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357901/
https://ncbi.nlm.nih.gov/pubmed/22301167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.etap.2011.12.027
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