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Modulation of iron metabolism in aging and in Alzheimer's disease: relevance of the choroid plexus
Iron is essential for mammalian cellular homeostasis. However, in excess, it promotes free radical formation and is associated with aging-related progressive deterioration and with neurodegenerative disorders such as Alzheimer's disease (AD). There are no mechanisms to excrete iron, which makes...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357636/ https://ncbi.nlm.nih.gov/pubmed/22661928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2012.00025 |
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