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Physiologically Based Toxicokinetic Modelling as a Tool to Support Risk Assessment: Three Case Studies

In this contribution we present three case studies of physiologically based toxicokinetic (PBTK) modelling in regulatory risk assessment. (1) Age-dependent lower enzyme expression in the newborn leads to bisphenol A (BPA) blood levels which are near the levels of the tolerated daily intake (TDI) at...

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Detalhes bibliográficos
Main Authors: Mielke, Hans, Gundert-Remy, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357559/
https://ncbi.nlm.nih.gov/pubmed/22649449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/359471
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