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Deletion of Beta‐2‐Microglobulin Ameliorates Spinal Cord Lesion Load and Promotes Recovery of Brainstem NAA Levels in a Murine Model of Multiple Sclerosis

We used genetic deletion of β2‐microglobulin to study the influence of CD8(+) T cells on spinal cord demyelination, remyelination, axonal loss and brainstem N‐acetyl aspartate levels during the acute and chronic phases of Theiler's murine encephalomyelitis virus (TMEV) infection. We used β2m(−/...

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Autors principals: Denic, Aleksandar, Pirko, Istvan, Wootla, Bharath, Bieber, Allan, Macura, Slobodan, Rodriguez, Moses
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357463/
https://ncbi.nlm.nih.gov/pubmed/22335434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00576.x
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