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Effects of Acute Tryptophan Depletion on Brain Serotonin Function and Concentrations of Dopamine and Norepinephrine in C57BL/6J and BALB/cJ Mice
Acute tryptophan depletion (ATD) is a method of lowering brain serotonin (5-HT). Administration of large neutral amino acids (LNAA) limits the transport of endogenous tryptophan (TRP) across the blood brain barrier by competition with other LNAAs and subsequently decreases serotonergic neurotransmis...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
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Public Library of Science
2012
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Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357407/ https://ncbi.nlm.nih.gov/pubmed/22629305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035916 |
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