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Effects of Acute Tryptophan Depletion on Brain Serotonin Function and Concentrations of Dopamine and Norepinephrine in C57BL/6J and BALB/cJ Mice

Acute tryptophan depletion (ATD) is a method of lowering brain serotonin (5-HT). Administration of large neutral amino acids (LNAA) limits the transport of endogenous tryptophan (TRP) across the blood brain barrier by competition with other LNAAs and subsequently decreases serotonergic neurotransmis...

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Detalhes bibliográficos
Main Authors: Biskup, Caroline Sarah, Sánchez, Cristina L., Arrant, Andrew, Van Swearingen, Amanda E. D., Kuhn, Cynthia, Zepf, Florian Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357407/
https://ncbi.nlm.nih.gov/pubmed/22629305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035916
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