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Asymmetric chromatid segregation in cardiac progenitor cells is enhanced by Pim-1 kinase

RATIONALE: Cardiac progenitor cells (CPCs) in the adult heart are used for cell-based treatment of myocardial damage but factors determining stemness, self-renewal and lineage commitment are poorly understood. Immortal DNA strands inherited through asymmetric chromatid segregation correlate with sel...

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Detalhes bibliográficos
Main Authors: Sundararaman, Balaji, Avitabile, Daniele, Konstandin, Mathias H, Cottage, Christopher T, Gude, Natalie, Sussman, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357328/
https://ncbi.nlm.nih.gov/pubmed/22441844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.267716
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