Skeletal Muscle Protein Tyrosine Phosphatase 1B Regulates Insulin Sensitivity in African Americans

Protein tyrosine phosphatase 1B (PTP1B) is postulated to modulate insulin action by dephosphorylating the insulin receptor signaling proteins and attenuating insulin signaling. We sought to determine the relationship of skeletal muscle PTP1B to whole-body insulin sensitivity. We studied 17 African A...

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Bibliographic Details
Main Authors: Stull, April J., Wang, Zhong Q., Zhang, Xian H., Yu, Yongmei, Johnson, William D., Cefalu, William T.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2012
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357297/
https://ncbi.nlm.nih.gov/pubmed/22474028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0744
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