α1-Acid Glycoprotein Decreases Neutrophil Migration and Increases Susceptibility to Sepsis in Diabetic Mice

The mechanisms underlying immune deficiency in diabetes are largely unknown. In the present study, we demonstrate that diabetic mice are highly susceptible to polymicrobial sepsis due to reduction in rolling, adhesion, and migration of leukocytes to the focus of infection. In addition, after sepsis...

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Detaylı Bibliyografya
Asıl Yazarlar: Spiller, Fernando, Carlos, Daniela, Souto, Fabrício O., de Freitas, Andressa, Soares, Fernanda S., Vieira, Silvio M., Paula, Francisco J.A., Alves-Filho, José C., Cunha, Fernando Q.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2012
Konular:
Complications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357278/
https://ncbi.nlm.nih.gov/pubmed/22415874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0825
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