Enhanced Cerebral but Not Peripheral Angiogenesis in the Goto-Kakizaki Model of Type 2 Diabetes Involves VEGF and Peroxynitrite Signaling

We previously reported enhanced cerebrovascular remodeling and arteriogenesis in experimental type 2 diabetes. This study tested the hypotheses that 1) cerebral but not peripheral angiogenesis is increased in a spatial manner and 2) peroxynitrite orchestrates vascular endothelial growth factor (VEGF...

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Detalhes bibliográficos
Main Authors: Prakash, Roshini, Somanath, Payaningal R., El-Remessy, Azza B., Kelly-Cobbs, Aisha, Stern, Javier E., Dore-Duffy, Paula, Johnson, Maribeth, Fagan, Susan C., Ergul, Adviye
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357273/
https://ncbi.nlm.nih.gov/pubmed/22403298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1528
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