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Patterns of placental development evaluated by X chromosome inactivation profiling provide a basis to evaluate the origin of epigenetic variation
BACKGROUND: Inactivation of the maternally or paternally derived X chromosome (XCI) initially occurs in a random manner in early development; however as tissues form, a ‘patchiness’ will occur in terms of which X is inactivated if cells positioned near each other are clonally descended from a common...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357192/ https://ncbi.nlm.nih.gov/pubmed/22431562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/des072 |
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