Staphylococcus aureus Virulence Is Enhanced by Secreted Factors That Block Innate Immune Defenses

Staphylococcus aureus is a leading human pathogen that causes a large variety of diseases. In vitro studies have shown that S. aureus secretes several small proteins that block specific elements of the host innate immune system, but their role in bacterial pathogenicity is unknown. For instance, the...

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Bibliographic Details
Main Authors: Jongerius, Ilse, von Köckritz-Blickwede, Maren, Horsburgh, Malcolm J., Ruyken, Maartje, Nizet, Victor, Rooijakkers, Suzan H.M.
Format: Artigo
Language:Inglês
Published: S. Karger AG 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357151/
https://ncbi.nlm.nih.gov/pubmed/22327617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000334604
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