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Genetic polymorphisms and obesity influence estradiol decline during the menopause

OBJECTIVES: Obesity and genetic variation in aromatase and type 1 17-β hydroxysteroid dehydrogenase (HSD) could influence the E2 trajectory of decline during the menopause transition. DESIGN AND PARTICIPANTS: E2 trajectories during the menopause transition (phenotype) were identified using 5934 data...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sowers, MaryFran R., Randolph, John F., Zheng, Huiyong, Jannausch, Mary, McConnell, Daniel, Kardia, Sharon R., Crandall, Carolyn J., Nan, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357071/
https://ncbi.nlm.nih.gov/pubmed/21198743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2265.2010.03968.x
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