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Characterization of a Disordered Protein During Micellation: Interactions of α-Synuclein with Sodium Dodecyl Sulfate
To better understand the interaction of α-Synuclein (αSyn) with lipid membranes, we carried out self-assembly molecular dynamics simulations of αSyn with monomeric and micellar sodium dodecyl sulfate (SDS), a widely used membrane mimic. We find that both electrostatic and hydrophobic forces contribu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357070/ https://ncbi.nlm.nih.gov/pubmed/22439820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp210339f |
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