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Structural Basis for Calcium and Phosphatidyl Serine Regulation of PLC δ1
Many membrane associated enzymes including those of the phospholipase C (PLC) superfamily are regulated by specific interactions with lipids. Previously we have shown that the C2 domain of PLC δ1 is required for phosphatidyl serine (PS) dependent enzyme activation, and that activation requires the p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356995/ https://ncbi.nlm.nih.gov/pubmed/22385159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201252f |
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