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Nucleotide-dependent mechanism of Get3 as elucidated from free energy calculations
The unique topology of tail-anchored (TA) proteins precludes them from utilizing the well-studied cotranslational translocation mechanism of most transmembrane proteins, forcing them into a distinct, posttranslational pathway. In yeast, this process is the guided entry of TA-proteins (GET) pathway,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356667/ https://ncbi.nlm.nih.gov/pubmed/22547793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117441109 |
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