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Caenorhabditis elegans POT-2 telomere protein represses a mode of alternative lengthening of telomeres with normal telomere lengths

Canonical telomere repeats at chromosome termini can be maintained by a telomerase-independent pathway termed alternative lengthening of telomeres (ALT). Human cancers that survive via ALT can exhibit long and heterogeneous telomeres, although many telomerase-negative tumors possess telomeres of nor...

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Autori principali: Cheng, Chen, Shtessel, Ludmila, Brady, Megan M., Ahmed, Shawn
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356646/
https://ncbi.nlm.nih.gov/pubmed/22547822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119191109
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