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Induction of mucosal HIV-specific B and T cell responses after oral immunization with live coxsackievirus B4 recombinants

Given the limited success of clinical HIV vaccine trials, new vaccine strategies are needed for the HIV pipeline. The present study explored the novel concept that a live enteric virus, with limited disease potential, is a suitable vaccine vector to elicit HIV-specific immune responses in the gut mu...

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Detalhes bibliográficos
Main Authors: Gu, Rui, Stagnar, Cristy, Zaichenko, Lesya, Ramsingh, Arlene I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356479/
https://ncbi.nlm.nih.gov/pubmed/22464964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.03.034
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