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Molecular Analysis of the Noggin (NOG) Gene in Holoprosencephaly Patients

Holoprosencephaly (HPE) is the most common structural anomaly of the human forebrain. Various genetic and teratogenic causes have been implicated in its pathogenesis. A recent report in mice described Noggin (NOG) as a candidate gene involved in the etiogenesis of microform HPE. Here, we present for...

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Main Authors: Srivastava, Kshitij, Hu, Ping, Solomon, Benjamin D., Ming, Jeffrey E., Roessler, Erich, Muenke, Maximilian
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356444/
https://ncbi.nlm.nih.gov/pubmed/22503063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2012.03.008
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