Cell Wall Trapping of Autocrine Peptides for Human G-Protein-Coupled Receptors on the Yeast Cell Surface

G-protein-coupled receptors (GPCRs) regulate a wide variety of physiological processes and are important pharmaceutical targets for drug discovery. Here, we describe a unique concept based on yeast cell-surface display technology to selectively track eligible peptides with agonistic activity for hum...

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Bibliografiske detaljer
Main Authors: Ishii, Jun, Yoshimoto, Nobuo, Tatematsu, Kenji, Kuroda, Shun’ichi, Ogino, Chiaki, Fukuda, Hideki, Kondo, Akihiko
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356411/
https://ncbi.nlm.nih.gov/pubmed/22623985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037136
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