Daily Rhythms of Plasma Melatonin, but Not Plasma Leptin or Leptin mRNA, Vary between Lean, Obese and Type 2 Diabetic Men

Melatonin and leptin exhibit daily rhythms that may contribute towards changes in metabolic physiology. It remains unclear, however, whether this rhythmicity is altered in obesity or type 2 diabetes (T2DM). We tested the hypothesis that 24-hour profiles of melatonin, leptin and leptin mRNA are alter...

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Detalhes bibliográficos
Main Authors: Mäntele, Simone, Otway, Daniella T., Middleton, Benita, Bretschneider, Silvia, Wright, John, Robertson, M. Denise, Skene, Debra J., Johnston, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356389/
https://ncbi.nlm.nih.gov/pubmed/22623983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037123
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