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Erythroid Promoter Confines FGF2 Expression to the Marrow after Hematopoietic Stem Cell Gene Therapy and Leads to Enhanced Endosteal Bone Formation
Fibroblast growth factor-2 (FGF2) has been demonstrated to be a promising osteogenic factor for treating osteoporosis. Our earlier study shows that transplantation of mouse Sca-1(+) hematopoietic stem/progenitor cells that are engineered to express a modified FGF2 leads to considerable endosteal/tra...
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主要な著者: | , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2012
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356341/ https://ncbi.nlm.nih.gov/pubmed/22629419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037569 |
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