Isocorydine Inhibits Cell Proliferation in Hepatocellular Carcinoma Cell Lines by Inducing G2/M Cell Cycle Arrest and Apoptosis

The treatment of human hepatocellular carcinoma (HCC) cell lines with (+)-isocorydine, which was isolated and purified from Papaveraceae sp. plants, resulted in a growth inhibitory effect caused by the induction of G2/M phase cell cycle arrest and apoptosis. We report that isocorydine induces G2/M p...

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Main Authors: Sun, Hefen, Hou, Helei, Lu, Ping, Zhang, Lixing, Zhao, Fangyu, Ge, Chao, Wang, Tingpu, Yao, Ming, Li, Jinjun
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356335/
https://ncbi.nlm.nih.gov/pubmed/22623962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036808
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