Analysis of Detailed Phenotype Profiles Reveals CHRNA5-CHRNA3-CHRNB4 Gene Cluster Association With Several Nicotine Dependence Traits

INTRODUCTION: The role of the nicotinic acetylcholine receptor gene cluster on chromosome 15q24-25 in the etiology of nicotine dependence (ND) is still being defined. In this study, we included all 15 tagging single nucleotide polymorphisms (SNPs) within the CHRNA5-CHRNA3-CHRNB4 cluster and tested a...

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Dades bibliogràfiques
Autors principals: Broms, Ulla, Wedenoja, Juho, Largeau, Marine R., Korhonen, Tellervo, Pitkäniemi, Janne, Keskitalo-Vuokko, Kaisu, Häppölä, Anja, Heikkilä, Katri H., Heikkilä, Kauko, Ripatti, Samuli, Sarin, Antti-Pekka, Salminen, Outi, Paunio, Tiina, Pergadia, Michele L., Madden, Pamela A. F., Kaprio, Jaakko, Loukola, Anu
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Original Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356294/
https://ncbi.nlm.nih.gov/pubmed/22241830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntr283
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