Co-encapsulation of magnetic Fe(3)O(4) nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery

In this study, the authors constructed a novel PLGA [poly(D,L-lactic-co-glycolic acid)]-based polymeric nanocarrier co-encapsulated with doxorubicin (DOX) and magnetic Fe(3)O(4) nanoparticles (MNPs) using a single emulsion evaporation method. The DOX-MNPs showed high entrapment efficiency, and they...

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Bibliografiske detaljer
Main Authors: Jia, Yanhui, Yuan, Mei, Yuan, Huidong, Huang, Xinglu, Sui, Xiang, Cui, Xuemei, Tang, Fangqiong, Peng, Jiang, Chen, Jiying, Lu, Shibi, Xu, Wenjing, Zhang, Li, Guo, Quanyi
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2012
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356178/
https://ncbi.nlm.nih.gov/pubmed/22619520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S28629
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