Influence of pH on the Cytotoxic Activity of Inositol Hexakisphosphate (IP6) in Prostate Cancer

Objectives: In the present study, we investigated whether the pH of IP6 could influence its anti-tumoral activity in vitro. Methods: PC-3 cells were exposed to IP6 at pH 5, pH 7, and pH 12 and we evaluated the metabolic activity (WST-1 assay), cell proliferation (cell count), cell cycle distribution...

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Bibliografiska uppgifter
Huvudupphovsmän: Betton, Blandine, Gannon, Philippe O., Koumakpayi, Ismaël Hervé, Diallo, Jean-Simon, Mes-Masson, Anne-Marie, Saad, Fred
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Research Foundation 2011
Ämnen:
Oncology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356122/
https://ncbi.nlm.nih.gov/pubmed/22655245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2011.00040
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