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Drug Discovery Opportunities and Challenges at G Protein Coupled Receptors for Long Chain Free Fatty Acids
Discovery of G protein coupled receptors for long chain free fatty acids (FFAs), FFA1 (GPR40) and GPR120, has expanded our understanding of these nutrients as signaling molecules. These receptors have emerged as important sensors for FFA levels in the circulation or the gut lumen, based on evidence...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355945/ https://ncbi.nlm.nih.gov/pubmed/22649399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2011.00112 |
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