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Stem cell heterogeneity: implications for aging and regenerative medicine

For decades, hematopoietic stem cells (HSCs) were thought to be a homogeneous population of cells with flexible behavior. Now a new picture has emerged: The HSC compartment consists of several subpopulations of HSCs each with distinct, preprogrammed differentiation and proliferation behaviors. These...

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Detalhes bibliográficos
Main Authors: Muller-Sieburg, Christa E., Sieburg, Hans B., Bernitz, Jeff M., Cattarossi, Giulio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355711/
https://ncbi.nlm.nih.gov/pubmed/22408258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-376749
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