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Exogenous GLP-2 and IGF-I induce a differential intestinal response in IGF binding protein-3 and -5 double knockout mice

Glucagon-like peptide-2 (GLP-2) action is dependent on intestinal expression of IGF-I, and IGF-I action is modulated by IGF binding proteins (IGFBP). Our objective was to evaluate whether the intestinal response to GLP-2 or IGF-I is dependent on expression of IGFBP-3 and -5. Male, adult mice in six...

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Detalhes bibliográficos
Main Authors: Murali, Sangita G., Brinkman, Adam S., Solverson, Patrick, Pun, Wing, Pintar, John E., Ney, Denise M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355561/
https://ncbi.nlm.nih.gov/pubmed/22281475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00372.2011
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