Endothelial cells create a stem cell niche in glioblastoma by providing Notch ligands that nurture self-renewal of cancer stem-like cells

One important function of endothelial cells in glioblastoma (GBM) is to create a niche that helps promote self-renewal of cancer stem-like cells (CSLCs). However, the underlying molecular mechanism for this endothelial function is not known. Since activation of Notch signaling has been found to be r...

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Detalhes bibliográficos
Main Authors: Zhu, Thant S., Costello, Mark A., Talsma, Caroline E., Flack, Callie G., Crowley, Jessica G., Hamm, Lisa L., He, Xiaobing, Hervey-J umper, Shawn L., Heth, Jason A., Muraszko, Karin M., DiMeco, Francesco, Vescovi, Angelo L., Fan, Xing
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355476/
https://ncbi.nlm.nih.gov/pubmed/21788346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4269
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