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REDUCING EXPRESSION OF GluN1(0XX) SUBUNIT SPLICE VARIANTS OF THE NMDA RECEPTOR INTERFERES WITH SPATIAL REFERENCE MEMORY

The GluN1 subunit of the NMDA receptor shows age-related changes in its expression pattern, some of which correlate with spatial memory performance in mice. Aged C57BL/6 mice show an age-related increase in mRNA expression of GluN1 subunit splice variants that lack the N terminal splice cassette, Gl...

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Autors principals: Das, Siba R., Jensen, Ross, Kelsay, Rian, Shumaker, Michelle, Bochart, Rachele, Brim, Brenna, Zamzow, Daniel, Magnusson, Kathy R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355246/
https://ncbi.nlm.nih.gov/pubmed/22360858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2012.02.014
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