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Stat3-mediated activation of miR-23a suppresses gluconeogenesis in hepatocellular carcinoma by downregulating G6PC and PGC-1α

Considerable effort has been made in elucidating the mechanism and functional significance of high levels of aerobic glycolysis in cancer cells, commonly referred to as Warburg effect. Here, we investigated whether gluconeogenic pathway is significantly modulated in hepatocarcinogenesis, resulting i...

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Detalhes bibliográficos
Main Authors: Wang, Bo, Hsu, Shuhao, Frankel, Wendy, Ghoshal, Kalpana, Jacob, Samson T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355233/
https://ncbi.nlm.nih.gov/pubmed/22318941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25632
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