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REDUCED METHYLATION OF THE THROMBOXANE SYNTHASE GENE IS CORRELATED WITH ITS INCREASED VASCULAR EXPRESSION IN PREECLAMPSIA

Preeclampsia is characterized by increased thromboxane and decreased prostacyclin levels, which predate symptoms, and can explain some of the clinical manifestations of preeclampsia, including hypertension and thrombosis. In this study, we examined DNA methylation of the promoter region of the throm...

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Detalhes bibliográficos
Main Authors: Mousa, Ahmad A., Strauss, Jerome F., Walsh, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355228/
https://ncbi.nlm.nih.gov/pubmed/22493072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.188730
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