CXCL13 Activation of c-Myc Induce RANK Ligand Expression in Stromal/Preosteoblast Cells in the Oral Squamous Cell Carcinoma Tumor-Bone Microenvironment

CXC chemokine ligand-13 (CXCL13) has been implicated in oral squamous cell carcinoma (OSCC) tumor progression and osteolysis. Tumor necrosis factor family member, RANKL (receptor activator of NF-κB ligand), a critical bone resorbing osteoclastogenic factor plays an important role in cancer invasion...

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Bibliographic Details
Main Authors: Sambandam, Yuvaraj, Sundaram, Kumaran, Liu, Angen, Kirkwood, Keith L., Ries, William L., Reddy, Sakamuri V.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355224/
https://ncbi.nlm.nih.gov/pubmed/22330139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.24
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